On July 8th, the section of the Development of Minimally and Non-invasive Medicine" was successfully held as part of the 5th Yangtze International Summit of Minimally invasive and Non-invasive Medicine initiated, 2023 Belt and Road Micro-invasive Medicine Innovation Forum.

This part was jointly chaired by Li Qilong (from Taiwan, China), Chairman of the Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapeutics (APAGE),Yang Hanfeng, the Party secretary of Hospital of North Sichuan Medical College, David Cranston, President of the International Society of Minimally Invasive and Virtue Surgery (ISMIVS), Chen Chunlin, Director of Obstetrics and Gynecology at Nanfang Hospital of Southern Medical University, Zhang Lian, President of Chongqing Haifu Hospital, Vitaya Titapant, President of the Royal Thai College of Obstetricians and Gynaecologists, Chen Guoqiang, President of First People's Hospital of Foshan, Xing Ruoxi, Professor at Chongqing Medical University, and Relly Yanuari Primariawan, Council Member of the Asia-Pacific Association of Gynecologic Endoscopy and Minimally Invasive Therapeutics (APAGE).

A total of 10 experts shared their brilliant lectures on "the Development of Minimally and Non-invasive Medicine"and jointly explored cutting-edge technologies in the field of minimally and non-invasive medicine, lightening a path to the bright future of minimally and non-invasive medicine.

David Cranston, chairman of the International society of minimally invasive and virtue surgery (ISMIVS) and professor at the University of Oxford, gave a special lecture titled "in the steps of William Osler and the development of noninvasive medicine" Throughout the development of medicine, William Osler believed that "diseases that harm the human body require treatment methods that cause less harm to the body". Focusing ultrasound ablation technology is currently the best way to put this belief into practice, and it has been clinically proven to be a safe, effective and minimally invasive solution.

Chairman of the China-Australia-Asia Pacific Minimally Invasive Surgery Forum and Professor at the University of New South Wales, Felix Wong, Shares a Special Lecture on "Focused ultrasound surgery-potential new direction." He shared the practical applications of focused ultrasound thermal ablation and non-thermal mechanical ablation, as well as the future directions and prospects of HIFU treatment.

"Former President and Current Director of the European Society for Gynaecological Endoscopy (ESGE), Rudy Leon De Wilde, shared a special lecture on "Forget the Surgical Therapy in Adenomyosis." Focused ultrasound ablation therapy for adenomyosis has undergone evidence-based clinical research and multicenter prospective studies. With numerous clinical experiences, it has rapidly developed, demonstrating good safety and effectiveness comparable to minimally invasive surgery.

Professor Xin Shelley Wang from the Department of Symptom Research at The University of Texas MD Anderson Cancer Center shares a special lecture on the 'Utility of ePROs in Postoperatice Care.' In team-based cancer care models, electronic patient-reported outcomes (ePRO) serve as a comprehensive monitoring tool for all healthcare participants, providing management and monitoring of adverse reactions, complications, functional status, and psychological state throughout the entire cancer treatment process. The ePRO system offers additional functionalities, including rapid aggregation of individual symptom items and symptom scales, quantification and standardization of self-reported data, longitudinal patient tracking surveys for long-term analysis.

Chairman of the Board of Directors of the Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapy (APAGE), Lee Chyilong, shared a special lecture on the ' the necessity of the certification in non-minimal invasive therapy'. High-Intensity Focused Ultrasound (HIFU) was first developed in Chongqing. Guided by ultrasound, the technology uses high-intensity ultrasonic waves to selectively destroy fibroid tissue within the target area without damaging surrounding normal tissues, achieving minimally invasive treatment for uterine fibroids. This advantage of HIFU makes it one of the important trends of the future minimally invasive treatments. Safety certification requires rigorous scrutiny and assessment before comprehensive conclusions can be drawn from experimental trials.

Ø Director of the Department of Obstetrics and Gynecology at Nanfang Hospital of Southern Medical University, Chen Chunlin, shared a special lecture on the ‘Minimally invasive and noninvasive technology/artificial intelligence- future vision of diagnose and treatment obstetrics and gynecology disease’. Focused Ultrasound Ablation Surgery (FUAS) can eliminate periodic pain associated with adenomyosis. By ablating the thickened lesions in the myometrium and reducing the lesion area of endometriosis, ectopic endometrial function is removed,

Consequently, the uterine environment for conception is improved and fertility promoted. Additionally, the lecture also explores the integration of minimally invasive surgeries such as intervention and laparoscopy with artificial intelligence.

Chairman of Suining Central Hospital Medical Group, Chen Yongjun, shared a special lecture on 'Review and outlook: progress in the field of endoscopy and future of minimally invasive and noninvasive medicine.' The first generation of surgical procedures involved open surgery, followed by the second generation which introduced minimally invasive surgery. The third generation of surgical procedures involves super minimally invasive surgery, or even non-invasive surgery, such as high-intensity focused ultrasound. Analyzing the trends of change in medicine from the perspective of historical evolution, the lecture explores the future prospects of minimally invasive surgery.

Founder and Chairman of the Focused Ultrasound Foundation, Neal F. Kassell, shared a special lecture on "'Curing with sound" Revered as a "game-changer", focused ultrasound therapy is a highly disruptive non-invasive treatment technology. It has transformed the paradigm of disease treatment and holds the potential to become a revolutionary diagnostic tool, much like magnetic resonance imaging (MRI). There is ample scientific evidence indicating the effectiveness of focused ultrasound therapy. Every year, hundreds of peer-reviewed papers are published, showcasing the benefits of this technology, with papers containing clinical trial data appearing in top medical journals such as the New England Journal of Medicine and The Lancet.

Virginia University neurosurgeon Dr. Shayan Moosa shared a lecture on "clinical applications of focused ultrasound in the brain" The lecture introduces the clinical applications of focused ultrasound therapy in treating brain disorders.

Associate Chief Physician/Chief Physician of the Department of Obstetrics and Gynecology at Peking Union Medical College Hospital, Yu Xin, shared a special lecture on "A surgeon’s perspective on focused ultrasound therapy." The lecture emphasizes the importance of selecting treatment methods that maximize benefits and minimize harm. The best choice is the one that both doctors and patients agree upon. There is no single best method; there will always be room for improvement. It is not necessary to pursue or adhere to a specific approach. Every technique has its advantages and disadvantages, and it is important to complement each other's strengths and weaknesses.